Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum.

Dermaut B, Kumar-Singh S, Rademakers R, Theuns J, Cruts M, Van Broeckhoven C.

Trends Genet. 2005 Dec;21(12):664-72. doi: 10.1016/j.tig.2005.09.005. Epub 2005 Oct 10.

PMID: 16221505

Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample.

Rademakers R, Cruts M, Sleegers K, Dermaut B, Theuns J, Aulchenko Y, Weckx S, De Pooter T, Van den Broeck M, Corsmit E, De Rijk P, Del-Favero J, van Swieten J, van Duijn CM, Van Broeckhoven C.

Am J Hum Genet. 2005 Oct;77(4):643-52. doi: 10.1086/491749. Epub 2005 Aug 30.

PMID: 16175510 

Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer.

Dermaut B, Norga KK, Kania A, Verstreken P, Pan H, Zhou Y, Callaerts P, Bellen HJ.

J Cell Biol. 2005 Jul 4;170(1):127-39. doi: 10.1083/jcb.200412001.

PMID: 15998804

Genomic architecture of human 17q21 linked to frontotemporal dementia uncovers a highly homologous family of low-copy repeats in the tau region.

Cruts M, Rademakers R, Gijselinck I, van der Zee J, Dermaut B, de Pooter T, de Rijk P, Del-Favero J, van Broeckhoven C.

Hum Mol Genet. 2005 Jul 1;14(13):1753-62. doi: 10.1093/hmg/ddi182. Epub 2005 May 11.

PMID: 15888485